Diabetes. 20.8 million people in the U.S. (7% of the population) have diabetes. Researchers are studying how hypertension and diabetes affect the kidneys. …


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Donated Organs Fast Facts Current Research

| | | |
| |COPD | |
| |16 million adults in |Researchers are working on a device to|
| |the US are diagnosed |ease suffering of COPD by reducing |
|LUNGS |with COPD An |lung tidal volume, utilizing human |
| |additional 16 million |lungs to develop this amazing |
| |are estimated to live |technology |
| |with the disease |Current research studying gene therapy|
| |undiagnosed |for cystic fibrosis patients is |
| | |underway Researchers use diseased and|
| |Cystic fibrosis |non-diseased lung tissue in their |
| | |studies |
| |CF affects one out of |Oral therapies for asthma are being |
| |every 3,500
births in |researched focusing on receptors in |
| |the US annually |bronchial epithelium and smooth |
| | |muscle Animal models are not |
| |Asthma |predictable in studying this |
| |An estimated 205 |particular A1 receptor, thus human |
| |million Americans |donated tissue is essential to unlock |
| |suffer from Asthma; |potential treatments |
| |117 million of which | |
| |are children | |
| | | |
|HEART |Transplant preservation| |
| | | |
| |Since 1988, over 41,400|Researchers are working to improve |
| |heart transplants have |cardiac preservation times to extend |
| |taken place However, |the duration of cold ischemia time |
|
|2,700 people are still |enabling hearts to travel a greater |
| |waiting 2007 Organ |distance for transplant |
| |preservation limits the| |
| |distance between |Infrared imaging is being used to |
| |donated organs the |identify coronary plaque and identify |
| |recipient |type of plaque through non surgical |
| |Cardiovascular disease |means Donor hearts with CV disease |
| |Nearly 2,500 Americans |are needed in this study |
| |die of CVD each day; an| |
| |average of 1 death | |
| |every 35 seconds | |
| | | |
|PANCREAS |Diabetes |Researchers and transplant clinicians |
| |208 million people in |are working hard to perfect islet cell|
| |the US 7 of the |isolation and
transplantation Donor |
| |population have |pancreata are also important in |
| |diabetes |testing immunology and gene therapy |
| |1/3 of disease | |
| |sufferers remain | |
| |undiagnosed | |
| | | |
| | | |
| | | |
|INTESTINE |Drug absorption |Intestinal tissue is key in studying |
| |Hundreds of new drugs |drug absorption Proper drug dosing |
| |are tested each year to|must be tested before it is safe for |
| |improve human quality |human consumption |
| |of life and alleviate | |
| |disease symptoms | |
| |
| |
| |Hepatitis B C |Researchers utilize human liver tissue|
| |3-4 million Americans |to test new drug therapies focusing on|
|LIVER |are chronically |metabolism, toxicity enzyme |
| |infected with HCV |induction |
| |125 million Americans |All of these mentioned diseases may |
| |are chronically |potentially require liver |
| |infected with HBV |transplantation Ongoing research |
| |Liver Cancer |utilizes whole or partial livers |
| |500, 000 annual deaths |split in an attempt to isolate liver|
| |in the US are a |cells, called hepatocytes, with the |
| |result of primary liver|goal of transplanting the cells some |
| |cancer |day to alleviate the need for a whole |
| | |solid organ transplant for some |
| |Liver failure |patients |
|
|Liver injury is now the| |
| |leading cause of acute | |
| |liver failure in the |Studies are underway to determine the |
| |US |affects of the environment on our |
| | |liver |
| | | |
| |Chronic kidney disease |Researchers are studying how |
|KIDNEYS | renal failure |hypertension and diabetes affect the |
| |20 million US adults |kidneys By utilizing human kidney |
| |have chronic kidney |cells, they are developing compound |
| |disease which leads to |pharmaceuticals to treat heart and |
| |renal failure; the only|renal diseases |
| |treatment for kidney | |
| |failure is transplant |Toxin and carcinogen studies are |
| |or dialysis |performed to
determine if specific |
| | |environmental contaminants are toxic |
| | |to kidneys |
| | | |

Other possibilities
Researchers utilize many other organs and tissues in important studies:
Stomachs are often needed for studies in GERD
Aorta is involved in studying the genetics behind aortic aneurysms
Bladders are needed for the study of incontinence and development of
treatments for disorders of the bladder
We appreciate your referral of all non-transplantable organs
consented for research

1-800-486-IIAM 4426

Source:avondiabetes.nhs.uk

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