Community Diabetes Care Program/Project Dulce. a program in partnership with The Whittier Institute for Diabetes, a subsidiary of Scripps, is dedicated to …


December 2000

The Benefits of Giving
As the year draws to a close, now is a good time to consider the many options for year-end giving The holidays are a very special time to give charitable donations Here are a few options you might want to consider:
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You may donate your personal residence, live there for the rest of your life, and receive a lifetime fixed income based on the value of your home You will also receive an immediate income tax deduction for the contribution

Cash gifts may be deducted from your federal income tax return up to 50 percent of your adjusted gross income A gift of long-term appreciated securities lets you deduct the full fair market value of your investments and avoid any tax on the capital gain A gift of securities, or any appreciated property, is deductible up to 30 percent of your adjusted gross income

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For more information about how to advance diabetes care and make a tax-smart gift, call Roz Hodgins, Director of Development, at 8586265664

The Whittier Institute Board of Trustees Chairman: Maurice R Taylor II Vice Chairman: Gobind Sahney Corporate Secretary: Jackie Singer Treasurer: Bryce W Rhodes President/CEO: John B Engle David H Bartram
Earl K Beitzel Charles H Brandes Martin B Buser George E Dailey, III, MD Edward W Holmes, MD Vivian M Leith Robert F List John Messerschmitt Berlyn D Miller Don W Mitchell, Esq Jerrold M Olefsky, MD Margery A Perry Janet A Rodgers, PhD Charles E Scribner Richard R Sheridan, Esq Marilyn B Tedesco Honorary Trustees Richard C Atkinson, PhD Brian Bilbray Willard P VanderLaan, MD William C Winter, MD Scripps/UCSD/Whittier Diabetes Research Program Committee Scientific Director: Jerrold M Olefsky, MD Clyde H Beck, Jr, MD George E Dailey III, MD John B Engle Alberto Hayek, MD Kenneth L Jones, MD Stanley A Mendoza, MD George E Palade, MD Margery A Perry Bryce W Rhodes Richard R Sheridan, Esq Daniel Steinberg, MD Samuel SC Yen, MD Whittier Diabetes Program Principal Investigators Theodore Ciaraldi, PhD Vincenzo Cirulli, MD, PhD George E Dailey III, MD Wolfgang Dillmann, MD Steve V Edelman, MD Alberto Hayek, MD Robert R Henry, MD Yolanta Kruszynska, MD Fred Levine, MD, PhD Jerrold M Olefsky, MD Wulf Palinski, MD Athena Philis-Tsimikas, MD Henry C Powell, MD Peter D Reaven, MD David Rose, PhD Daniel Steinberg, MD Nicholas JGWebster, PhD Joseph L Witztum, MD Patricia Wu, MD

Sisters with a
Special Bond New Faces at the Whittier Diabetes and the Holidays Hearty White Chili

9894 Genesee Avenue La Jolla, California 92037 wwwwhittierorg

Non-profit organization US Postage

PAID
permit No 1981 San Diego, CA

Scripps Whittier Diabetes Program Scripps/UCSD/Whittier Diabetes Research Program Community Diabetes Care Program/Project Dulce a program in partnership with Community Health Improvement Partners
The Whittier Institute for Diabetes, a subsidiary of Scripps, is dedicated to diabetes research, education and patient care through a collaborative program with the University of California, San Diego

As you may have noticed, The Whittier Diabetes Report has a new look Weve combined The Whittier and Project Dulce newsletters, increasing our report to eight pages and expanding our readership We hope you like the changes and we welcome your comments or suggestions Send email to hodginsr@whittierorg

Jerrold M Olefsky, MD is currently Medical and Scientific Director of the Scripps/Whittier/UCSD Diabetes Program, as well as Professor of Medicine at UCSD and Research Scientist at the Veterans Medical Research Foundation

Donor Profile: Twin Sist ers Support Ea ch Other
Being
twins, Mollie and Jackie Singer share a special bond Another condition brings them even closer together You see, Mollie was diagnosed with juvenile diabetes, also known as Type1 diabetes, at the age of four For the past six months Mollie has successfully worn a MiniMed Insulin Pump Prior to the pump, Mollies daily ritual for the last six years included taking up to six shots of insulin, testing her blood sugar level an average of ten times, and then eating and playing according to the levels She no longer takes injections, but the rest of her disciplined life remains the same Not wanting her sister to go through the disease alone, the two 11-year-olds have banded together to take on diabetes They currently travel the country with their Mother, teaching the world about Mollies illness Not only have they spoken with politicians, doctors and researchers, they have testified at a Senate Hearing, written a short book entitled The Road to the Cure, and have formed a support group called Mollies DAs, or Diabetic Angels Even though the angels dont have diabetes themselves, they use their knowledge to assist in caring for someone who does or to educate others, including teachers and
parents
On the cover, Mollie left and Jackie Singer

Research Findings Lead to New Theory
Dr Jerrold Olefsky, Scientific Director of the Scripps/UCSD/Whittier Diabetes Research Program, along with his team of researchers know the number one rule of science question everything Yet, they were still surprised when all of their scientific tests didnt support a widely accepted theory as to how Type 2 diabetes drugs on the market work within the body Currently, there are two types of thiazolidinedione TZD insulin-sensitizing drugs on the market for treating Type 2 diabetes Actos and Avandia These TZDs attempt to overcome insulin resistance and make the diabetics tissues more able to respond to the insulin secreted from the pancreas A major challenge for the diabetes research community has been trying to explain precisely how these drugs work within the body A widely accepted belief has been that the diabetes drugs bind to a specific protein, called the PPAR gamma receptor, and this binding stimulates the production of a variety of genes that aid in overcoming insulin resistance The research team, consisting of Philip Miles, Yaacov Barak, Weiman He, Ronald Evans and Jerrold Olefsky,
decided to investigate this theory further Using the techniques of mouse genetics, they were able to manipulate genetic codes of mice and alter the genes Eventually, the PPAR gamma receptor gene was knocked out, which offered surprising results The mice without a PPAR gamma receptor were not insulin resistant, as was previously hypothesized Rather, the animals were extremely sensitive to insulin and were protected from diabetes To ensure the results were accurate, Dr Olefskys group repeated this particular experiment more than any other procedure in past research Yet, the test outcomes continued to remain the same, and the researchers finally came to the conclusion that the accepted theory was inaccurate Their evidence showed just the opposite diabetes drugs on the market do bind to the PPAR gamma receptor, but they more likely work by inhibiting the protein, not activating it as previously believed Within the last few months, this new theory has been supported by additional experiments, and outside laboratories have confirmed the results Armed with these new findings, the research community as well as pharmaceutical companies can create more effective drugs to combat diabetes In
fact, this will aid in finding drugs that not only improve insulin resistance, but also prevent Type 2 diabetes before its onset, which could then be administered to specific high-risk populations
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Contents:
Donor Profile: Twin Sisters 2 Research Findings Lead to a New Theory 3 Diabetes Support Groups 4 Managing Diabetes During the Holidays 4 Whittier Events 5 Hearty White Chili 6 New Faces at the Whittier 7 The Benefits of Giving 8

Twin sisters, Jackie left and Mollie Singer

Mission Statement:
The Whittier Institute for Diabetes supports the search to effect a cure for diabetes To accomplish this, The Whittier will provide resources for innovative research, education and patient care, and will be a catalyst for collaboration among other leading organizations engaged in these endeavors
Editor: Jodi Bakken Design: Leslie Gunn, This Gunn for Hire
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The twins mother, also named Jackie, tells the story of a nine year old girl whose grandfather went into diabetic shock at the Thanksgiving dinner table The girl was a Diabetic Angel and the only one in her family who knew what to do She saved her
grandfathers life because she chose to make a difference Over the years, as the Singer family learned more about diabetes research and admired the work done through the Whittier, Jackie decided to get more involved and contributed her time and public relations skills She currently serves as Corporate Secretary on The Whittier Board of Trustees People, even children, have the power to do so much, says Jackie Diabetes is not an individual disease it affects the whole family Just as families support

each other, we all need to support finding a cure for the 16 million Americans who currently live with diabetes Being a child with diabetes, Mollie has many obstacles to overcome that other kids her age take for granted For instance, when she gets sick, it takes her much longer to recover Once, due to illness, Mollie missed five weeks of school Yet, through extra hard work on her part, she was still able to maintain a 38 grade point average I try to take good care of myself and manage my diabetes so I can live my life to the fullest, but I can never take a vacation from my diabetes, says Mollie I really hope they find a cure for diabetes soon Im lucky because I have a special sister,
Jackie She makes life a lot of fun and makes living with diabetes easier together we can overcome anything When they are not traveling the country on a tireless mission, Mollie and Jackie enjoy roller blading, biking and visiting the beach to swim and ride the waves together

Whittier Walking Group:
By Maire Robacker Maire Robacker is a Certified Diabetes Educator with the Scripps Whittier Diabetes Program

A new group is starting that will travel

the walking track at Scripps Memorial Hospital La Jolla The group will meet every Wednesday at 12:30 pm in front of The Whittier Institute for Diabetes For further information, please call Connie Mehlman at 6192933720

Scripps Whittier Diabetes Program Support Groups
La Jolla:

The Whittier Institute for Diabetes 9894 Genesee Avenue, 3rd floor Campus of Scripps Memorial Hospital La Jolla
3rd Wednesday of the month 1:30 3 pm

Managing Diabetes During the Holidays
The holiday season can evoke mixed feelings for many people Some eagerly look forward to the holidays, while others are less enthusiastic and tend to feel stressed Diabetes can cause additional strain for both the diabetic and their families Daily routines may be disrupted with
parties, shopping and holiday events Developing a strategy to maintain good blood sugar control can help handle diabetes through the holiday season Try planning ahead rather than being reactive to a situation Do not shop when hungry, make conscious food choices and take extra insulin or increase your exercise if having a special treat Also, eat a bedtime snack at the usual dinnertime if planning a late meal Attention to medication is especially important this time of year If on insulin, check insulin-to-carbohydrate ratio to adequately cover yourself It might be necessary to check blood sugar more often Its easy to forget medications during evening activities Plan ahead with a selfreminder or keep extra medication in a pillbox and carry it along for later use Exercise lowers blood sugar and can greatly help maintain blood sugar control over the holiday season Engage in actives such as dancing, walking, skating or any other type of exercise that requires movement Do not give up even if you get off track for a few days It is never too late to start again Traveling across time zones can disrupt a schedule Talk to a doctor or diabetes educator about medication adjustments Be sure to
carry extra supplies since they may not be easy to find, especially when travelling abroad Also carry blood glucose monitoring supplies and medication in carry-on luggage, purchase a watch that displays time zones, and always wear a medic alert identification The holiday season can cause feelings of anger, sadness and depression for some people Attending a support group can help express those feelings while obtaining support from others May peace, hope and joy be yours this holiday season

Whittier Events
Golfing For a Great Cause
Theres nothing like a day of bright sunshine, fun friends and outstanding golf, well, pretty good golf anyway Those were the main ingredients at the 3rd Annual Dr Charles E Weber Invitational Golf Tournament benefiting The Whittier Institute for Diabetes The event was held at the La Jolla Country Club on Saturday, October 2, 2000 Following the tournament, Joe Jessop and David Gillig presented James Lewis Bowers, PhD with the Jessop Award for his many achievements in advancing the spirit of philanthropy within the community Silent and live auctions also highlighted the days events Over 13,000 was raised in the Fund-aDiabetic portion of the auction, which
will benefit the Community Diabetes Care Program All skill levels were welcomed to participate, and the event raised a grand total of 80,000 that will go toward supporting the diabetes

858 626-5659
Chula Vista:

Scripps Well Being Chula Vista 555 Broadway, Suite 2029
2nd Monday of the month 1:30 3 pm

858 626-5659
Chula Vista Spanish:

Principle Sponsor ResMed foursome: Amy Romaker, Deirdre Steward, Vance Wilson and Elliott Glick

Scripps Well Being Chula Vista 555 Broadway, Suite 2029
3rd Friday of the month 9 10:30 am

858 626-5659
Hillcrest:

programs at The Whittier Everyone agreed it was a great day of golf and plenty of fun

Scripps Mercy Hospital 4077 Fifth Avenue 3rd floor, Prenatal Conference Room
2nd Tuesday of the month 1:30 3 pm

Big Turnout for Annual Open House
The 4th Annual Diabetes Awareness Open House, hosted by The Whittier Institute for Diabetes, drew a big crowd on Saturday, November 11, 2000 The Open House, held in recognition of National Diabetes Awareness Month, featured a variety of displays highlighting new treatments in diabetes care, as well as free health screenings, exercise demonstrations, drawings and vendor displays Certified educators were on
hand to discuss issues of concern and dieticians were available to talk about calorie assessment and menu planning

619 260-7363
Encinitas:

Scripps Well Being Encinitas 270 N El Camino Real Vons Shopping Center
2nd Wednesday of the month 1:30 3 pm

858 792-8837
On-Line:
Diabetes Interview

wwwdiabetesintervieworg
Diabetes Self-Management

Keynote speakers included: Jeffrey Sandler, MD Diabetes and Research, Diane Pearson, RN, CDE Get Moving, Get Motivated and Jennifer Torio-Hurley, Certified Personal Trainer Exercise Can Be Fun

wwwdiabetes-self-mgmtcom
American Diabetes Association

wwwdiabetesorg
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We like to host this Open House every year to give the community a chance to receive valuable diabetes education, states John Engle, CEO of The Whittier Institute for Diabetes Thanks to the help of the many volunteers who dedicated their time selflessly, this years Open House was more successful than ever
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Calculated Cooking by Jeanne Jones

White Chili
Jeanne Jones has been involved with The Whittier Institute for Diabetes since 1981, when she was named the first president of Whittier Friends She was diagnosed with Type 2 diabetes in her 30s After the initial
shock wore off, Jeanne learned to control her diabetes through an exchange diet and has parlayed her success into a promising career Jeanne has written numerous books about light cuisine, appeared on national television programs, and is an internationally renowned nutrition consultant Her syndicated weekly column, Cook it Light, reaches millions of readers Jeanne, along with her mother, Kathryn Fishback, and her sister, Cheryl Harris, established the Kathryn C Fishback Family Foundation Their foundation has contributed handsomely to ongoing research and other projects at The Whittier Institute This hearty and easy to make chili is perfect for fall parties of all types or just a great family meal It is easily transported for tailgate events or potluck dinners, and is great to serve for buffetstyle parties as well It can be made up ahead of time at your convenience and stored, tightly covered, in the refrigerator Also, leftover chili freezes well for a quick meal in the future Use a heavy saucepan to cook the white chili In a lightweight pan the liquid boils too quickly, even over low heat If there is too much liquid left when the chili has finished cooking, stir and let it stand,
uncovered, until it cools slightly much of the liquid will be absorbed Then reheat to serve Ingredients youll need: 1 pound dried Great Northern beans, picked over, soaked overnight in water with a cover, and drained 4 cups fat free chicken stock 2 medium onions, coarsely chopped 3 cups 3 garlic cloves, pressed or minced 1/2 teaspoon salt 1 can 4 ounces chopped green California chilies 2 teaspoons ground cumin 1-1/2 teaspoons dried oregano, crushed 1 teaspoon ground coriander 1/4 teaspoon ground cloves 1/4 teaspoon cayenne pepper or to taste 3 ounces low-fat Monterey jack cheese, grated 3/4 cup optional 1 Combine the beans, stock, 1-1/2 cups of the onions, garlic, and salt in a large heavy pot or saucepan and bring to a boil Reduce the heat to low, cover, and simmer for 2 hours or until the beans are very tender, adding more stock if needed 2 When the beans are tender, add the remaining 1-1/2 cups of onion, the chilies and all of the seasonings and mix well Continue to cook, covered, for an additional 30 minutes 3 To serve, spoon 1 cup of the chili into individual bowls and top each serving with 2 tablespoons of Monterey jack cheese, if desired Makes 6 servings Each 1 cup serving
contains approximately: Calories: 322, Grams of fat: 3, Cholesterol: 8 mg, Sodium: 479 mg, Carbohydrates: 51 grams, Protein: 21 grams, Fiber: 1 gram Diabetic Exchange: 3-1/2 carbohydrates, 3 protein/meat and 1 fat

New Faces at The Whittier Institute
A New Researcher
Dr Nai-Wen Chi recently relocated from Boston, where he was an instructor in medicine at Harvard Medical School and a visiting scientist at MIT The UCSD Research Program is happy to welcome this newest member of the research team Dr Chi received his MD from Taiwan prior to immigrating to the United States twelve years ago While in Boston, he earned a PhD in biochemistry from Harvard University and completed his clinical training in internal medicine and endocrinology at the Massachusetts General Hospital In his new role, Dr Chi will focus on the cause of Type 2 diabetes By understanding the etiology of diabetes at the molecular level, we hope to identify novel targets for anti-diabetic drugs, he states, adding that hes proud to be a part of this team in the fight against diabetes Dr Chi lives in Carmel Valley with his wife and two sons, ages eight and six In their spare time, he likes to take his family swimming

New
Board Members
Charles Chuck Scribner recently joined The Whittier Institute Board of Trustees Mr Scribner is retired from Bank of America and lives in La Jolla with his wife, Gerry, to whom he has been married for over 40 years They have one adult son, Mark, who lives in Sun Valley, Idaho Diabetes is something that hits particularly close to home for Scribner Many family members have been afflicted with the disease, including his son and two sisters, one of whom eventually died as a result of diabetes Scribner became familiar with the Whittier while on the Scripps Board of Trustees for seven years, serving a term as Chairman of the Board He developed a closer relationship with staff members when his son, who was diagnosed with Type 1 diabetes at the age of 15, wanted to try the diabetes pump Even though Scribner is involved in many other community programs, he decided to devote time to serving on the Whittier Board of Trustees He is interested in helping the underserved populations and moving forward with city and county programs that support these members of the community David Bartram is also a new member of the Whittier Board of Trustees and attended his first meeting in
November Mr Bartram, an Executive Vice President at US Bank formerly COO Bank of Commerce, lives in Poway with his wife, Tamie, and two young daughters, Kirstin and Mackenzie, who was diagnosed with Type 1 diabetes at age four In their spare time, the family enjoys skiing, golfing, youth soccer and going to the beach Wanting to find out all that he could about the disease that afflicted his young daughter, Bartram became familiar with the Whittier and its role in the community He has been involved with the Whittier for the last three years as a sponsor of the annual golf tournament, raising funds through his company After meeting others involved, Bartram decided to take a more active role in supporting the Whittier mission and joined the Board of Trustees He is particularly interested in supporting diabetes research in the pursuit of a cure

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Source:whittier.org

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